Endocrine Abstracts

Introduction: In a US study of general practitioners, 50%-60% of their working time was found to be dedicated to paperwork and electronic medical record-keeping (including electronic prescription – EPC writing)1.Aim: Given the mandatory use of EPC in Greece, we wanted to assess the time required for this in the daily practice of our outpatient endocrinology clinic.Method: In one of the outpatient (OUP) clinics of t...

Background: Cases of combined primary aldosteronism and preclinical Cushing’s syndrome are reported extremely rare.Highlight of a report: An unusual case of hyperaldosteronism due to bilateral macronodular adenomas with a left renal mass in a 55-year-old male is presented. MRI scan of the abdomen revealed a 4.5 cm mass of the right adrenal and two nodules in the left adrenal sized 2 and 3 cm, respectively in diameter. Additionally, a large mass on t...

Introduction/Aim: Disease awareness days are numerous and varied [1]. In the present study we tried to assess the short-term impact of the 2017 diabetes awareness day in Greece by examining localized relevant internet-based searches.Materials/Methods: We collected data from Google TrendsTM regarding relative [internet] search volumes (RSVs) with key words “diabetes” (in Greek and English; study group) and “breast cancer” (a...

Papillary thyroid carcinoma is a disease associated with a very good prognosis. However, there are some subtypes of papillary thyroid cancer which are associated with aggressive biological behavior and worse outcome. The appearance of brain metastatic disease in the course of papillary thyroid carcinoma is rare and carries an unfavorable prognosis.The aim was to describe the case of a patient with tall cell papillary thyroid carcinoma who presented with ...

Ectopic Cushing's syndrome is rare, accounting for 5–10% of all cases of Cushing's. The majority are casued by small cell lung cancer and neuroendocrine tumours.We report a case of a 59 year old male who presented with osmotic symptoms after newly diagnosed diabetes, hypokalaemia and metabolic alkalosis with clinical features suggestive of Cushing's. Initial random cortisol was >2000 nmol/l and 24 hour urin...

Ectopic Cushing's syndrome is rare, accounting for 5–10% of all cases of Cushing's. The majority are casued by small cell lung cancer and neuroendocrine tumours.We report a case of a 59 year old male who presented with osmotic symptoms after newly diagnosed diabetes, hypokalaemia and metabolic alkalosis with clinical features suggestive of Cushing's. Initial random cortisol was >2000 nmol/l and 24 hour urin...

Introduction: Adrenal incidentalomas (AIs) are increasingly being identified due to more frequent use of cross-sectional imaging modalities. Recent studies reported AIs being identified in 7.3% of abdominal CT imaging. Most adrenal incidentalomas are adenomas that may have secretory activity.Case Report: An 80-year-old lady presented to our Emergency department with one week’s history of worsening right eye bulging and discomfort. She was found to h...

A 30-year-old lady was initially seen in our clinic with a slight elevated corrected calcium with an elevated parathyroid hormone in March 2021. The elevated calcium [2.58mmol/l(NR: 2.10-2.55)] was first noted in 2018 when she had investigations for easy bruising, fatigue, breathlessness, and weight loss. The symptoms settled on their own and her calcium levels were monitored routinely. She was referred to our clinic when the corrected calcium had increased to 2.69mmol/lwith a...

Background: Adipose tissue blood flow (ATBF) is important for delivering nutrients and oxygen to adipose tissue (AT), and distributing adipokines and metabolites into the circulation. ATBF has been measured with the 133Xenon wash-out technique (gold standard), microdialysis, laser Doppler Fluximetry, and contrast-enhanced ultrasound. However, due to decline in world-wide 133Xenon production and the invasive nature of other techniques, an alternative metho...

Introduction: Multiple endocrine neoplasia type 2 (MEN2) is an autosomal dominant disorder with an estimated prevalence of 1 per 30,000 in the general population. MEN2 is subclassified into two distinct syndromes: types 2A (MEN2A) and 2B (MEN2B). MEN2A and 2B are inherited in an autosomal dominant pattern with very high penetrance. In both syndromes, there is an occurrence of multicentric tumour formation in all organs where the RET proto-oncogene is expressed.<p ...